Does jogging make you itch? I remember those mile runs in grade school when my thighs would end up with a strange tingly itchy slightly swollen feeling and covered with faint pink blotches. Turns out that this is a condition called vibratory urticaria. It’s caused by mast cells which get stimulated by vibration to release histamine and other contents. In this case the histamine and contents inside of mast cells leads to itching, swelling and redness. While many people report vibratory urticaria happening with jogging, it can also occur when operating machinery such as lawnmowers, jackhammers, etc. I just have a mild case of vibratory urticaria. Some people can develop more intense swelling or a life-threatening condition called anaphylaxis with exercise. Rise in body temperature itself can also cause urticaria (hives) and occlusion of hair follicles after exercise can cause folliculitis. So there are all sorts of skin conditions that can happen with exercise!